Barça coach Pedro will be sacked after 21 years with the club, the club announced on Wednesday.
A statement from the club read: “The club is in a state of shock and we would like to extend our deepest condolences to the Barça family and friends.
The Club wishes Pedro and his family all the best in their future.”
The announcement came a day after Barça’s 2-0 win at Granada, and a day before the start of their Champions League qualifier with Sevilla.
Barcelona have won five of their last six Champions League qualifiers, having started the league campaign with four consecutive wins.